You can use liquid plant fertilizer with a ratio of 5:10:5. To avoid shocking your succulent, make sure the fertilizer is slow-release. It can be given fertilizer in spring or summer depending on its growth seasons. You can leave it alone for the rest. It is better to dilute the fertilizer with 50% strength soluble house plant food. Although you can fertilize your plant as many times as necessary, most plants can only be fed one time per year. The University of California, Davis says that the plant's sap can cause skin irritation and dermatitis to pets and humans.