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Osteoporosis - Cannabis Compound Hardens Bone
Yet another research paper recently been published that shows how plant based compounds are able to assist containing the brittle bone disease, osteoporosis. Experts in the Institute of Medical Sciences, Faculty of Aberdeen, UK have found the way a non-psychoactive compound of cannabis, cannabidiol helps to maintain bone strength.
The endocannabinoid system is a team of cellular receptors that are set off by a group of endogenous lipids along with nutrients derived from the cannabis plant. The cannabinoid receptors are engaged in a wide variety of physiological processes including appetite control, discomfort, memory and mood. Current research has shown that the endocannabinoid system has also a strong influence on bone metabolism, as the receptors are nicely represented on osteoclasts - cells whose major job is to resorb (thin out) bone.
Bone is an energetic, living tissue which is going to be continuously formed, remodeled as well as formed in reaction to both physical and physiological requirements of the body. Bone matrix consists primarily of the macronutrients calcium, magnesium and phosphate and it is the material which helps make up both the dense components of the bone as well as the bone marrow framework. Many people still think that if a person eats foods rich in these minerals then they will avoid developing osteoporosis. epidemiological and Other evidence suggests that this's not always the truth.
With regards to bone health as well as disease the integrated processes that control the development as well as resorption bone are quite as significant as the availability of calcium, phosphate and magnesium.
The formation as well as resorbtion of bone matrix is managed by two principal cellular types:
1) Osteoblasts are bone cells that are accountable for the formation of bone matrix 2) Osteoclasts are modified white blood cells responsible eagle hemp cbd gummies for sale (simply click the up coming article) the resorption of bone tissue.
Osteoblasts
Osteoclasts
These two cell types are controlled by an elaborate set of signaling hormones, proteins as well as cellular receptors that react to the ever-changing requirements on bone tissue along with other physiological processes. If there are too many osteoclasts, or if these cells become overactive, they will resorb more matrix compared to the osteoblasts are able to produce. A predominance of osteoclast activity results in the bone becoming much less dense - the primary characteristic of the medical condition known as osteoporosis.
The Aberdeen researchers have discovered that cannabidiol binds to a certain cannabinoid receptor on the bone-resorbing osteoblast cells. By so doing it prevents these cells from resorbing the bone matrix - thereby helping to prevent further weakening of the bones.
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