The FDA calculated the price of Good Manufacturing Practices (GMP) whenever they first drafted the Dietary Supplement Health and Education Act (DSHEA). Dietary product GMP regulations, located in the Federal Register, cover everything estimated costs, concerning compliance, that a company would incur depending on business size. The FDA estimated that altogether dietary supplement makers would invest 56,000 hours as a one-time burden in development of written methods. Additionally, 930,000 hours was estimated as the sum total for exipure reviews trustpilot uk those business enterprises to conduct proper record keeping. The FDA then used this data to estimate the economic impact for a variety of sized companies.

Cost per Establishment by Size

Small Establishments (Less than 20 employees with annual revenue below $1M)

Small Establishments

Set up Costs = $26,000

Annual Costs = $46,000

Moderate Establishments (twenty - 500 staff with annual revenue of $5M - $10M)

Medium Establishments

Set up Costs = $20,000

Yearly Costs = $184,000