The care of this succulent is simple even for beginner gardeners. It's one the most popular plants for new plant owners. Although succulents can be picky about the soil they like, it is best to use a mixture that is capable of draining water. This is because succulents don't thrive in soil that's too moist. These symptoms could indicate that your devil's backbone plant poisonous to humans needs more water than it should, or that root rot may be present.